Courses

Topics in surface chemistry and thin film growth with focus on atomic layer deposition (ALD) and molecular layer deposition (MLD). Properties of thin films grown using ALD and MLD. Applications of thin films in areas including flexible displays, energy storage and catalysis. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Treats current topics in the spectrocscopy of ions. Seminar lectures are given by graduate students on their research and on literature topics, and the results of both in-house and external research groups are studied. Additionally, ideas for interesting directions of research and new experiments are proposed and discussed. May be repeated up to 2 total credit hours. Prereq., graduate standing or instructor consent. Prerequisites: Restricted to Graduate Students only.

Topics in various aspects of current research; emphasizes student readings and presentations. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Discussion of experimental and theoretical approaches for probing structures and dynamics of proteins, peptides, and nucleic acids; and computations in molecular dynamics simulation, modeling, and geometry. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Discusses and reviews the current literature and experimental results in signal transduction, cell cycle and tumor suppressor gene regulation. Emphasizes the understandings of molecular and biochemical mechanisms of the origin of human tumor cells. Prereq., graduate standing or instructor consent. Prerequisites: Restricted to Graduate Students only.

Topics in various aspects of current biochemical and environmental research. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Study of the mechanisms of eukaryotic gene expression with an emphasis on the structure and function of human mediator transcription complexes. Restricted to graduate students or instructor consent. Prerequisites: Restricted to Graduate Students only.

Discussion of advances and developments in biomolecular dynamics, with emphasis on experimental studies via ultrafast laser spectroscopy. The connection of protein dynamics with function will also be considered. Restricted to graduate students or instructor consent required. Prerequisites: Restricted to Graduate Students only.

Discusses recent results and current literature in the areas of the mechanism of sensory proteins, internal motions of proteins, and protein folding. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Studies experimental approaches to understand the mechanisms of enzymic catalysis. Techniques include steady-state and pre-steady-state kinetics, isotope trapping and partitioning, inhibition by substrate analogues, and covalent modification of proteins.May be repeated up to 6 total credit hours. Prereq.,instructor consent. Prerequisites: Restricted to Graduate Students only.

Discussion of advances and developments in biomolecular dynamics, with emphasis on experimentalstudies via ultrafast laser spectroscopy. The connection of protein dynamics with function will also be considered. Restricted to graduate students or instructor consent required. Prerequisites: Restricted to Graduate Students only.

Devoted to experimental methods for understanding mechanisms of signal transduction in mammalian cells through pathways involving regulation of protein phosphorylation. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Studies structure and folding of proteins and protein complexes using biophysical methods, including nuclear magnetic resonance (NMR), circular dichroism, and fluorescence spectroscopies. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Studies the regulation of transcription by RNA Polymerase II from human promoters. May be repeated up to 6 total credit hours. Prereq., instructor consent. Prerequisites: Restricted to Graduate Students only.

Discussion of advances and developments in structural biology with emphasis on new methods for protein expression, purification and crystallization; and structure solution implementation. Prereq., graduate standing or instructor consent. Prerequisites: Restricted to Graduate Students only.

Studies aspects of the biochemical and structural analysis of ribonucleic acid (RNA) and its interactions with proteins and assemblies into functional ribonucleoprotein (RNP) enzymes. Techniques focus on x-ray crystallography, spectroscopic methods, and biochemical probing. Prereq., graduate standing or instructor consent. Prerequisites: Restricted to Graduate Students only.

All doctoral students must register for 30 hours of dissertation credit as part of the requirements for the degree. For a detailed discussion of doctoral dissertation credit, refer to the Graduate School section. Prerequisites: Restricted to Graduate Students only.